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PUBLICATIONS

Most recent publications by the Nanomedicine and Molecular Imaging group’s members

Muñoz-Hernando, M.; Nogales, P.; Fernández-Barahona, I.; Ruiz-Cabello. J.; Bentzon J. F.; Herranz, F. Sphingomyelinase-responsive nanomicelles for targeting atherosclerosisNanoscale2024, 10.1039/D3NR06507C.

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Arroyo-Urea, E. M.; Lázaro-Díez, M.; Garmendia, J.; Herranz, F.; González-Paredes, A. Lipid-Based Nanomedicines for the Treatment of Bacterial Respiratory Infections: Current State and New Perspectives. Nanomedicine, 2024, nnm-2023-0243.

Asensio-López, J.; Lázaro-Díez, M.; Hernández-Cruz, T.M.; Blanco-Cabra, N.; Sorzabal-Bellido, I.; Arroyo-Urea, E. M.; Buetas, E.; et al. Multimodal Evaluation of Drug Antibacterial Activity Reveals Cinnamaldehyde Analog Anti-Biofilm Effects against Haemophilus Influenzae. Biofilm 2024, 7, 100178.

Ibáñez-Moragues, M.; Fernández-Barahona, I.; Santacruz, R.; Oteo, M.; Luján-Rodríguez, V. M.; Muñoz-Hernando, M.; Magro, N. et al. Zinc-Doped Iron Oxide Nanoparticles as a Proton-Activatable Agent for Dose Range Verification in Proton Therapy. Molecules 2023, 28, 19, 6874.

Martínez-Parra, L.; Piñol-Cancer, M.; Sanchez-Cano, C.; Miguel-Coello, A.B.; Di Silvio, D.; Gomez, A.M.; Uriel, C. et al. A Comparative Study of Ultrasmall Calcium Carbonate Nanoparticles for Targeting and Imaging Atherosclerotic Plaque. ACS Nano 2023, 17, 14, 13811.

Pellico, J.; Ruiz-Cabello, J.; Herranz, F. Radiolabeled Iron Oxide Nanomaterials for Multimodal Nuclear Imaging and Positive Contrast Magnetic Resonance Imaging (MRI): A Review. ACS Applied Nano Materials 2023, 6, 22, 20523.

Ceron, C.; Casquero‐Veiga, M.; Fernandez‐Barahona, I.; Muñoz‐Hernando, M.; Fernandez‐Nueda, I., Fuster, V., Moro, M.A.; Herranz, F.; Cortes‐Canteli, M. In Vivo Nanotracer for the Detection of Brain Thrombi in an AD Mouse Model. Alzheimer’s & Dementia 2023, 19, S16: e073660.

Arroyo-urea, E. M.; Muñoz-Hernando, M.; Leo-Barriga, M.; Herranz, F.; González-Paredes, A. A quality by design approach for the synthesis of palmitoyl carnitine loaded nanoemulsions as drug delivery systems. Drug Delivery2023, 30, 1, 2179128.

Martí-María, O.; Martínez-Gualda, B.; Fernández-Barahona, I.; Mills, A.; Abdelnabi; R.; Noppen, S.; Neyts, J.; Schols, D.; Camarasa, M.J.; Herranz, F.; Gago, F.; San-Félix, A. Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors. Eur. J. Med. Chem. 2022, 237, 114414.

Grzelak, J.; Gázquez, J.; Grayston, A.;  Teles, M.; Herranz, F.; Roher, N.; Rosell, A.; Roig, A., Gich, M. Magnetic Mesoporous Silica Nanorods Loaded with Ceria and Functionalized with Fluorophores for Multimodal Imaging. ACS Appl. Nano Mater. 2022, 5, 2, 2113.

Carregal-Romero, S.; Groult, H.; Cañadas, O.; Gonzalez, N.; Lechuga-Vieco, A..; García-Fojeda, B.; Herranz, F.; Pellico, J.; Hidalgo, A.; Casals, C.; Ruiz-Cabello, J. Delayed alveolar clearance of nanoparticles through control of coating composition and interaction with lung surfactant protein A  Biomaterials Advances 2022, 112551

Pellico, J.; Fernández-Barahona, I.; Ruiz-Cabello, J.; Gutiérrez, L.; Muñoz-Hernando, M.; Sánchez-Guisado, M.J.; Aiestaran-Zelaia, I.; Martínez-Parra, L.; Rodríguez, I.; Bentzon, J. and Herranz, F. HAP-Multitag, a PET and Positive MRI Contrast Nanotracer for the Longitudinal Characterization of Vascular Calcifications in Atherosclerosis. ACS Applied Materials & Interfaces 2021, 13, 45279−45290.

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Díez-Villares, S.; Pellico, J.; Gómez-Lado, N.; Grijalvo, S.; Alijas, S.; Eritja, R.; Herranz, F.; Aguiar, P.; de la Fuente, M. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging. International J. of Nanomedicine 2021 :16 5923–5935

Mazarío, E.; Cañete, M.; Herranz, F.; Sánchez-Marcos, J.; de la Fuente, J.M.; Herrasti, P. and Menéndez, N. Highly Efficient T2 Cobalt Ferrite Nanoparticles Vectorized for Internalization in Cancer CellsPharmaceuticals2021, 14, 124.

Cogliati, S.; Herranz, F.; Ruiz-Cabello, J.; Enríquez, J. A. Digitonin concentration is determinant for mitochondrial supercomplexes analysis by BlueNative PageBBA – Bioenergetics2021, 1862, 148332.

Adrover, J.M.; Pellico, J.; Fernández-Barahona, I.; Martín-Salamanca, S.; Ruiz-Cabello, J.; Hidalgo, A. and Herranz, F. Thrombo-tag, an in vivo formed nanotracer for the detection of thrombi in mice by fast pre-targeted molecular imagingNanoscale2020, 12, 22978-22987.

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García-Soriano, D.; Amaro, R.; La fuente-Gómez, N.; Milán-Rois, P., Somoza, A.; Navío, C.; Herranz, F.; Gutiérrez, L.; Salas, G. The influence of cation incorporation and leaching in the properties of Mn-doped nanoparticles for biomedical applicationsJ. Colloid and Interface Science2020, 15, 510-521.

Fernández-Afonso, I.; Salas, G.; Fernández-Barahona, I.; Herranz, F.; Grüttner, C.; Martínez de la Fuente, J.; Morales, M.P. and Gutiérrez, L. Smartphone-Based Colorimetric Method to Quantify Iron Concentration and to Determine the Nanoparticle Size from Suspensions of Magnetic NanoparticlesPart. Part. Syst. Charact2020, 2000032.

Fernández-Barahona, I.; Muñoz-hernando, M.; Ruiz-cabello, J.; Herranz, F.; Pellico, J. Iron Oxide Nanoparticles : An Alternative for Positive Contrast in Magnetic Resonance ImagingInorganics 2020, 1–22.

Velasco, C.; Mota-Cobián, A.; Mota, R.A.; Pellico, J.; Herranz, F.; Galán-Arriola, C.; Ibáñez, B.; Ruiz-Cabello, J.; Mateo, J.; España, S. Quantitative assessment of myocardial blood flow and extracellular volume fraction using 68Ga-DOTA-PET: A feasibility and validation study in large animals. J. Nuclear Cardiology 202027, 1249–1260.

Fernández-Barahona, I.; Muñoz-Hernando, M.; Herranz, F. Microwave-Driven Synthesis of Iron-Oxide Nanoparticles for Molecular ImagingMolecules 2019, 24, 1224.

Luengo, Y.; Roldan, M.A; Varela, M.; Herranz, F.; Morales, M.P.; Veintemillas-Verdaguer, S.; Doped-Iron Oxide Nanocrystals Synthesized by One-Step Aqueous Route for Multi-Imaging PurposesJ. Phys. Chem. C 2019, 123 (12), 7356–7365.

Fernández-Barahona, I.; Gutiérrez, L.; Veintemillas-Verdaguer, S.; Pellico, J.; Morales, M.P.; Catala, M.; del Pozo, M.A.; Ruiz-Cabello, J.; Herranz F. Cu-Doped Extremely Small Iron Oxide Nanoparticles with Large Longitudinal Relaxivity: One-Pot Synthesis and in Vivo Targeted Molecular Imaging. ACS Omega. 2019, 4 (2), 2719–2727.

Pellico, J.; Fernández-Barahona, I.; Benito, M.; Gaitán-Simón, A.; Gutiérrez, L.; Ruiz-Cabello, J.; Herranz F. Unambiguous detection of atherosclerosis using bioorthogonal nanomaterialsNanomedicine: Nanotechnology, Biology and Medicine. 2019, 17, 26-35.

Pellico, J.; Lechuga-Vieco, A.V.; Almarza, E.; Hidalgo, A.; Mesa-Nuñez, C.; Fernández-Barahona, I.; Quintana, J.A.; Bueren, J.; Enríquez, J.A.; Ruiz-Cabello, J.; Herranz, F. Molecular Imaging with Nanoparticles: specific in vivo detection of  neutrophils. Arch Bronconeumol. 2018, 54(Espec Cong 3):1-7

Fernández-Barahona, I.; Ruiz-Cabello, J.; Herranz, F.; Pellico, J. Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging. doi:10.3791/58269. J. Vis. Exp. 141, e58269, 2018. doi:10.3791/58269.  https://www.jove.com/embed/player?id=58269&t=1&s=1

Groult, H.; García-Álvarez, I.; Romero-Ramírez, L.; Nieto-Sampedro, M.; Herranz, F.; Fernández-Mayoralas, A.; Ruiz-Cabello, J. Micellar Iron Oxide Nanoparticles Coated with Anti-Tumor GlycosidesNanomaterials 2018, 8, 567.

Fernández-Barahona, I.; Muñoz-Hernando, I.; Pellico, J.; Ruiz-Cabello, J.; Herranz F.  Molecular Imaging with 68Ga Radio-Nanomaterials: Shedding Light on Nanoparticles  Applied Sciences 2018 8(7), 1098; doi: 10.3390/app8071098

Lechuga-Vieco, A. V.; Groult, H.; Pellico, J.; Mateo, J.; Enríquez, J. A.; Ruiz-Cabello, J.; Herranz, F. Protein Corona and Phospholipase Activity Drive Selective Accumulation of Nanomicelles in Atherosclerotic PlaquesNanomedicine: Nanotechnology, Biology and Medicine. 201814 (3), 643–650.

Pellico, J.; Llop, J.; Fernández-Barahona, I.; Bhavesh, R.; Ruiz-Cabello, J.; Herranz, F. Iron Oxide Nanoradiomaterials: Combining Nanoscale Properties with Radioisotopes for Enhanced Molecular ImagingContrast Media Mol. Imaging 20172017, 1–24.

Pellico, J.; Ruiz-Cabello, J.; Fernández-Barahona, I.; Gutiérrez, L.; Lechuga-Vieco, A. V.; Enríquez, J. A.; Morales, M. P.; Herranz, F. One-Step Fast Synthesis of Nanoparticles for MRI: Coating Chemistry as the Key Variable Determining Positive or Negative ContrastLangmuir 201733 (39), 10239–10247.

Velasco, C.; Mateo, J.; Santos, A.; Mota-Cobian, A.; Herranz, F.; Pellico, J.; Mota, R. A.; España, S.; Ruiz-Cabello, J. Assessment of Regional Pulmonary Blood Flow Using 68Ga-DOTA PET. EJNMMI Res. 20177 (1), 7.

Pellico, J.; Lechuga-Vieco, A. V.; Almarza, E.; Hidalgo, A.; Mesa-Nuñez, C.; Fernández-Barahona, I.; Quintana, J. A.; Bueren, J.; Enríquez, J. A.; Ruiz-Cabello, J.; Herranz, F. In Vivo Imaging of Lung Inflammation with Neutrophil-Specific 68Ga Nano-RadiotracerSci. Rep. 20177 (1), 13242.

Groult, H.; Poupard, N.; Herranz, F.; Conforto, E.; Bridiau, N.; Sannier, F.; Bordenave, S.; Piot, J.-M.; Ruiz-Cabello, J.; Fruitier-Arnaudin, I.; Maugard, T. Family of Bioactive Heparin-Coated Iron Oxide Nanoparticles with Positive Contrast in Magnetic Resonance Imaging for Specific Biomedical ApplicationsBiomacromolecules 201718 (10), 3156–3167.

Herranz, F.; Morales, M. P.; Rodríguez, I.; Ruiz-Cabello, J. Iron Oxide Nanoparticle-Based MRI Contrast Agents: Characterization and In Vivo Use. In Magnetic Characterization Techniques for Nanomaterials; Springer Berlin Heidelberg: Berlin, Heidelberg, 2017; pp 85–120.

Pellico, J.; Ruiz-Cabello, J.; Saiz-Alía, M.; del Rosario, G.; Caja, S.; Montoya, M.; Fernández de Manuel, L.; Morales, M. P.; Gutiérrez, L.; Galiana, B.; Enríquez, J. A.; Herranz, F. Fast Synthesis and Bioconjugation of 68 Ga Core-Doped Extremely Small Iron Oxide Nanoparticles for PET/MR ImagingContrast Media Mol. Imaging 201611 (3), 203–210.

Marciello, M.; Pellico, J.; Fernandez-barahona, I.; Herranz, F.; Ruiz-cabello, J.; Filice, M.; Ine, S. J. Recent Advances in the Preparation and Application of Multifunctional Iron Oxide and Liposome-Based Nanosystems for Multimodal Diagnosis and TherapyInterface Focus 2016.

Zahraei, M.; Marciello, M.; Lazaro-Carrillo, A.; Villanueva, A.; Herranz, F.; Talelli, M.; Costo, R.; Monshi, A.; Shahbazi-Gahrouei, D.; Amirnasr, M.; Behdadfar, B.; Morales, M. P. Versatile Theranostics Agents Designed by Coating Ferrite Nanoparticles with Biocompatible PolymersNanotechnology 201627 (25), 255702.

Pellico, J.; Ruiz-Cabello, J.; Herranz, F. Microwave-Driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of AtherosclerosisJ. Vis. Exp. 2016, No. 109.

Groult, H.; Ruiz-Cabello, J.; Pellico, J.; Lechuga-Vieco, A. V.; Bhavesh, R.; Zamai, M.; Almarza, E.; Martín-Padura, I.; Cantelar, E.; Martínez-Alcázar, M. P.; Herranz, F. Parallel Multifunctionalization of Nanoparticles: A One-Step Modular Approach for in Vivo ImagingBioconjug. Chem. 201526 (1), 153–160.

Pellico, J.; Lechuga-Vieco, A. V.; Benito, M.; García-Segura, J. M.; Fuster, V.; Ruiz-Cabello, J.; Herranz, F. Microwave-Driven Synthesis of Bisphosphonate Nanoparticles Allows in Vivo Visualisation of Atherosclerotic PlaqueRSC Adv. 20155 (3), 1661–1665.

Salinas, B.; Ruiz-Cabello, J.; Lechuga-Vieco, A. V.; Benito, M.; Herranz, F. Surface-Functionalized Nanoparticles by Olefin Metathesis: A Chemoselective Approach for In Vivo Characterization of Atherosclerosis PlaqueChem. – A Eur. J. 201521 (29), 10450–10456.

Bhavesh, R.; Lechuga-Vieco, A.; Ruiz-Cabello, J.; Herranz, F. T1-MRI Fluorescent Iron Oxide Nanoparticles by Microwave Assisted SynthesisNanomaterials 20155 (4), 1880–1890.

Groult, H.; Ruiz-Cabello, J.; Lechuga-Vieco, A. V.; Mateo, J.; Benito, M.; Bilbao, I.; Martínez-Alcázar, M. P.; Lopez, J. A.; Vázquez, J.; Herranz, F. Phosphatidylcholine-Coated Iron Oxide Nanomicelles for In Vivo Prolonged Circulation Time with an Antibiofouling Protein CoronaChem. – A Eur. J. 201420 (50), 16662–16671.

Herranz, F.; Salinas, B.; Groult, H.; Pellico, J.; Lechuga-Vieco, A.; Bhavesh, R.; Ruiz-Cabello, J. Superparamagnetic Nanoparticles for Atherosclerosis ImagingNanomaterials 20144 (2), 408–438.

Herranz F., Pérez-Medina C., Bilbao I., Benito M., Ibañez B., Fuster V.; Ruiz-Cabello J. Nanoplatform-Based Cardiovascular Molecular Imaging. In Nanotechnology; 2013.

Farrán, A.; Mohanraj, J.; Clarkson, G. J.; Claramunt, R. M.; Herranz, F.; Accorsi, G. Tuning Photoinduced Processes of Covalently Bound Isoalloxazine and Anthraquinone BichromophoresPhotochem. Photobiol. Sci. 201312 (5), 813–822.

Ruiz, A.; Salas, G.; Calero, M.; Hernández, Y.; Villanueva, A.; Herranz, F.; Veintemillas-Verdaguer, S.; Martínez, E.; Barber, D. F.; Morales, M. P. Short-Chain PEG Molecules Strongly Bound to Magnetic Nanoparticle for MRI Long Circulating AgentsActa Biomater. 20139 (5), 6421–6430.

Salinas, B.; Ruiz-Cabello, J.; Morales, M. P.; Herranz, F. Olefin Metathesis for the Functionalization of Superparamagnetic NanoparticlesBioinspired, Biomim. Nanobiomaterials 20121 (3).

Herranz, F.; Schmidt-Weber, C. B.; Shamji, M. H.; Narkus, A.; Ruiz-Cabello, J.; Vilar, R. Superparamagnetic Iron Oxide Nanoparticles Conjugated to a Grass Pollen Allergen and an Optical ProbeContrast Media Mol. Imaging 20127 (4), 435–439.

Veintemillas-Verdaguer, S.; Morales, M. P.; Serna, C. J.; Andrés-Vergés, M.; Ruiz-Cabello, J.; Herranz, F. Uniform Magnetite Nanoparticles Larger than 20 Nm Synthesized by an Aqueous Route. In Springer Proceedings in Physics; 2012; Vol. 140.

Herranz, F.; Pellico, J.; Ruiz-Cabello, J. Covalent Functionalization of Magnetic Nanoparticles for Biomedical ImagingSPIE Newsroom 2012.

Abbasi, A. Z.; Gutiérrez, L.; Del Mercato, L. L.; Herranz, F.; Chubykalo-Fesenko, O.; Veintemillas-Verdaguer, S.; Parak, W. J.; Morales, M. P.; González, J. M.; Hernando, A.; De La Presa, P. Magnetic Capsules for NMR Imaging: Effect of Magnetic Nanoparticles Spatial Distribution and AggregationJ. Phys. Chem. C 2011115 (14), 6257–6264.

Herranz, F.; Almarza, E.; Rodríguez, I.; Salinas, B.; Rosell, Y.; Desco, M.; Bulte, J. W.; Ruiz-Cabello, J. The Application of Nanoparticles in Gene Therapy and Magnetic Resonance ImagingMicrosc. Res. Tech. 201174 (7), 577–591.