Most recent publications by the Nanomedicine and Molecular Imaging group’s members


(5) Adrover, J.M.; Pellico, J.; Fernández-Barahona, I.; Martín-Salamanca, S.; Ruiz-Cabello, J.; Hidalgo, A. and Herranz, F. Thrombo-tag, an in vivo formed nanotracer for the detection of thrombi in mice by fast pre-targeted molecular imaging. Nanoscale. 2020, 12, 22978-2298710.1039/D0NR04538A

(4) Cogliati, S.; Herranz, F.; Ruiz-Cabello, J.; Enríquez, J. A. Digitonin concentration is determinant for mitochondrial supercomplexes analysis by BlueNative Page. BBA – Bioenergetics. 2020, 10.1016/j.bbabio.2020.148332.

(3) García-Soriano, D.; Amaro, R.; La fuente-Gómez, N.; Milán-Rois, P., Somoza, A.; Navío, C.; Herranz, F.; Gutiérrez, L.; Salas, G. The influence of cation incorporation and leaching in the properties of Mn-doped nanoparticles for biomedical applications. J. Colloid and Interface Science. 2020, 10.1016/j.jcis.2020.06.011.

(2) Fernández-Afonso, I.; Salas, G.; Fernández-Barahona, I.; Herranz, F.; Grüttner, C.; Martínez de la Fuente, J.; Morales, M.P. and Gutiérrez, L. Smartphone-Based Colorimetric Method to Quantify Iron Concentration and to Determine the Nanoparticle Size from Suspensions of Magnetic Nanoparticles. Part. Part. Syst. Charact. 2020, 2000032.

(1) Fernández-Barahona, I.; Muñoz-hernando, M.; Ruiz-cabello, J.; Herranz, F.; Pellico, J. Iron Oxide Nanoparticles : An Alternative for Positive Contrast in Magnetic Resonance Imaging. Inorganics 2020, 1–22.


(5) Velasco, C.; Mota-Cobián, A.; Mota, R.A.; Pellico, J.; Herranz, F.; Galán-Arriola, C.; Ibáñez, B.; Ruiz-Cabello, J.; Mateo, J.; España, S. Quantitative assessment of myocardial blood flow and extracellular volume fraction using 68Ga-DOTA-PET: A feasibility and validation study in large animals. J. Nuclear Cardiology 2019, doi: 10.1007/s12350-019-01694-z.

(4) Fernández-Barahona, I.; Muñoz-Hernando, M.; Herranz, F. Microwave-Driven Synthesis of Iron-Oxide Nanoparticles for Molecular Imaging. Molecules 2019, 24, 1224.

(3) Luengo, Y.; Roldan, M.A; Varela, M.; Herranz, F.; Morales, M.P.; Veintemillas-Verdaguer, S.; Doped-Iron Oxide Nanocrystals Synthesized by One-Step Aqueous Route for Multi-Imaging PurposesJ. Phys. Chem. C 2019, 123 (12), 7356–7365.

(2) Fernández-Barahona, I.; Gutiérrez, L.; Veintemillas-Verdaguer, S.; Pellico, J.; Morales, M.P.; Catala, M.; del Pozo, M.A.; Ruiz-Cabello, J.; Herranz F. Cu-Doped Extremely Small Iron Oxide Nanoparticles with Large Longitudinal Relaxivity: One-Pot Synthesis and in Vivo Targeted Molecular Imaging. ACS Omega. 2019, 4 (2), 2719–2727.

(1) Pellico, J.; Fernández-Barahona, I.; Benito, M.; Gaitán-Simón, A.; Gutiérrez, L.; Ruiz-Cabello, J.; Herranz F. Unambiguous detection of atherosclerosis using bioorthogonal nanomaterialsNanomedicine: Nanotechnology, Biology and Medicine. 2019, 17, 26-35.


(5) Pellico, J.; Lechuga-Vieco, A.V.; Almarza, E.; Hidalgo, A.; Mesa-Nuñez, C.; Fernández-Barahona, I.; Quintana, J.A.; Bueren, J.; Enríquez, J.A.; Ruiz-Cabello, J.; Herranz, F. Molecular Imaging with Nanoparticles: specific in vivo detection of  neutrophils. Arch Bronconeumol. 2018, 54(Espec Cong 3):1-7

(4) Fernández-Barahona, I.; Ruiz-Cabello, J.; Herranz, F.; Pellico, J. Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging. doi:10.3791/58269. J. Vis. Exp. 141, e58269, 2018. doi:10.3791/58269.

(3) Groult, H.; García-Álvarez, I.; Romero-Ramírez, L.; Nieto-Sampedro, M.; Herranz, F.; Fernández-Mayoralas, A.; Ruiz-Cabello, J. Micellar Iron Oxide Nanoparticles Coated with Anti-Tumor Glycosides. Nanomaterials 2018, 8, 567.

(2) Fernández-Barahona, I.; Muñoz-Hernando, I.; Pellico, J.; Ruiz-Cabello, J.; Herranz F.  Molecular Imaging with 68Ga Radio-Nanomaterials: Shedding Light on Nanoparticles  Applied Sciences 2018 8(7), 1098; doi: 10.3390/app8071098

(1) Lechuga-Vieco, A. V.; Groult, H.; Pellico, J.; Mateo, J.; Enríquez, J. A.; Ruiz-Cabello, J.; Herranz, F. Protein Corona and Phospholipase Activity Drive Selective Accumulation of Nanomicelles in Atherosclerotic Plaques. Nanomedicine: Nanotechnology, Biology and Medicine. 2018, 14 (3), 643–650.


(6) Pellico, J.; Llop, J.; Fernández-Barahona, I.; Bhavesh, R.; Ruiz-Cabello, J.; Herranz, F. Iron Oxide Nanoradiomaterials: Combining Nanoscale Properties with Radioisotopes for Enhanced Molecular Imaging. Contrast Media Mol. Imaging 2017, 2017, 1–24.

(5) Pellico, J.; Ruiz-Cabello, J.; Fernández-Barahona, I.; Gutiérrez, L.; Lechuga-Vieco, A. V.; Enríquez, J. A.; Morales, M. P.; Herranz, F. One-Step Fast Synthesis of Nanoparticles for MRI: Coating Chemistry as the Key Variable Determining Positive or Negative Contrast. Langmuir 2017, 33 (39), 10239–10247.

(4) Velasco, C.; Mateo, J.; Santos, A.; Mota-Cobian, A.; Herranz, F.; Pellico, J.; Mota, R. A.; España, S.; Ruiz-Cabello, J. Assessment of Regional Pulmonary Blood Flow Using 68Ga-DOTA PET. EJNMMI Res. 2017, 7 (1), 7.

(3) Pellico, J.; Lechuga-Vieco, A. V.; Almarza, E.; Hidalgo, A.; Mesa-Nuñez, C.; Fernández-Barahona, I.; Quintana, J. A.; Bueren, J.; Enríquez, J. A.; Ruiz-Cabello, J.; Herranz, F. In Vivo Imaging of Lung Inflammation with Neutrophil-Specific 68Ga Nano-Radiotracer. Sci. Rep. 2017, 7 (1), 13242.

(2) Groult, H.; Poupard, N.; Herranz, F.; Conforto, E.; Bridiau, N.; Sannier, F.; Bordenave, S.; Piot, J.-M.; Ruiz-Cabello, J.; Fruitier-Arnaudin, I.; Maugard, T. Family of Bioactive Heparin-Coated Iron Oxide Nanoparticles with Positive Contrast in Magnetic Resonance Imaging for Specific Biomedical Applications. Biomacromolecules 2017, 18 (10), 3156–3167.

(1) Herranz, F.; Morales, M. P.; Rodríguez, I.; Ruiz-Cabello, J. Iron Oxide Nanoparticle-Based MRI Contrast Agents: Characterization and In Vivo Use. In Magnetic Characterization Techniques for Nanomaterials; Springer Berlin Heidelberg: Berlin, Heidelberg, 2017; pp 85–120.


(4) Pellico, J.; Ruiz-Cabello, J.; Saiz-Alía, M.; del Rosario, G.; Caja, S.; Montoya, M.; Fernández de Manuel, L.; Morales, M. P.; Gutiérrez, L.; Galiana, B.; Enríquez, J. A.; Herranz, F. Fast Synthesis and Bioconjugation of 68 Ga Core-Doped Extremely Small Iron Oxide Nanoparticles for PET/MR Imaging. Contrast Media Mol. Imaging 2016, 11 (3), 203–210.

(3) Marciello, M.; Pellico, J.; Fernandez-barahona, I.; Herranz, F.; Ruiz-cabello, J.; Filice, M.; Ine, S. J. Recent Advances in the Preparation and Application of Multifunctional Iron Oxide and Liposome-Based Nanosystems for Multimodal Diagnosis and Therapy. Interface Focus 2016.

(2) Zahraei, M.; Marciello, M.; Lazaro-Carrillo, A.; Villanueva, A.; Herranz, F.; Talelli, M.; Costo, R.; Monshi, A.; Shahbazi-Gahrouei, D.; Amirnasr, M.; Behdadfar, B.; Morales, M. P. Versatile Theranostics Agents Designed by Coating Ferrite Nanoparticles with Biocompatible Polymers. Nanotechnology 2016, 27 (25), 255702.

(1) Pellico, J.; Ruiz-Cabello, J.; Herranz, F. Microwave-Driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of Atherosclerosis. J. Vis. Exp. 2016, No. 109.


(4) Groult, H.; Ruiz-Cabello, J.; Pellico, J.; Lechuga-Vieco, A. V.; Bhavesh, R.; Zamai, M.; Almarza, E.; Martín-Padura, I.; Cantelar, E.; Martínez-Alcázar, M. P.; Herranz, F. Parallel Multifunctionalization of Nanoparticles: A One-Step Modular Approach for in Vivo Imaging. Bioconjug. Chem. 2015, 26 (1), 153–160.

(3) Pellico, J.; Lechuga-Vieco, A. V.; Benito, M.; García-Segura, J. M.; Fuster, V.; Ruiz-Cabello, J.; Herranz, F. Microwave-Driven Synthesis of Bisphosphonate Nanoparticles Allows in Vivo Visualisation of Atherosclerotic Plaque. RSC Adv. 2015, 5 (3), 1661–1665.

(2) Salinas, B.; Ruiz-Cabello, J.; Lechuga-Vieco, A. V.; Benito, M.; Herranz, F. Surface-Functionalized Nanoparticles by Olefin Metathesis: A Chemoselective Approach for In Vivo Characterization of Atherosclerosis Plaque. Chem. – A Eur. J. 2015, 21 (29), 10450–10456.

(1) Bhavesh, R.; Lechuga-Vieco, A.; Ruiz-Cabello, J.; Herranz, F. T1-MRI Fluorescent Iron Oxide Nanoparticles by Microwave Assisted Synthesis. Nanomaterials 2015, 5 (4), 1880–1890.


(2) Groult, H.; Ruiz-Cabello, J.; Lechuga-Vieco, A. V.; Mateo, J.; Benito, M.; Bilbao, I.; Martínez-Alcázar, M. P.; Lopez, J. A.; Vázquez, J.; Herranz, F. Phosphatidylcholine-Coated Iron Oxide Nanomicelles for In Vivo Prolonged Circulation Time with an Antibiofouling Protein Corona. Chem. – A Eur. J. 2014, 20 (50), 16662–16671.

(1) Herranz, F.; Salinas, B.; Groult, H.; Pellico, J.; Lechuga-Vieco, A.; Bhavesh, R.; Ruiz-Cabello, J. Superparamagnetic Nanoparticles for Atherosclerosis Imaging. Nanomaterials 2014, 4 (2), 408–438.


(3) Herranz F., Pérez-Medina C., Bilbao I., Benito M., Ibañez B., Fuster V.; Ruiz-Cabello J. Nanoplatform-Based Cardiovascular Molecular Imaging. In Nanotechnology; 2013.

(2) Farrán, A.; Mohanraj, J.; Clarkson, G. J.; Claramunt, R. M.; Herranz, F.; Accorsi, G. Tuning Photoinduced Processes of Covalently Bound Isoalloxazine and Anthraquinone Bichromophores. Photochem. Photobiol. Sci. 2013, 12 (5), 813–822.

(1) Ruiz, A.; Salas, G.; Calero, M.; Hernández, Y.; Villanueva, A.; Herranz, F.; Veintemillas-Verdaguer, S.; Martínez, E.; Barber, D. F.; Morales, M. P. Short-Chain PEG Molecules Strongly Bound to Magnetic Nanoparticle for MRI Long Circulating Agents. Acta Biomater. 2013, 9 (5), 6421–6430.


(4) Salinas, B.; Ruiz-Cabello, J.; Morales, M. P.; Herranz, F. Olefin Metathesis for the Functionalization of Superparamagnetic Nanoparticles. Bioinspired, Biomim. Nanobiomaterials 2012, 1 (3).

(3) Herranz, F.; Schmidt-Weber, C. B.; Shamji, M. H.; Narkus, A.; Ruiz-Cabello, J.; Vilar, R. Superparamagnetic Iron Oxide Nanoparticles Conjugated to a Grass Pollen Allergen and an Optical Probe. Contrast Media Mol. Imaging 2012, 7 (4), 435–439.

(2) Veintemillas-Verdaguer, S.; Morales, M. P.; Serna, C. J.; Andrés-Vergés, M.; Ruiz-Cabello, J.; Herranz, F. Uniform Magnetite Nanoparticles Larger than 20 Nm Synthesized by an Aqueous Route. In Springer Proceedings in Physics; 2012; Vol. 140.

(1) Herranz, F.; Pellico, J.; Ruiz-Cabello, J. Covalent Functionalization of Magnetic Nanoparticles for Biomedical Imaging. SPIE Newsroom 2012.


(2) Abbasi, A. Z.; Gutiérrez, L.; Del Mercato, L. L.; Herranz, F.; Chubykalo-Fesenko, O.; Veintemillas-Verdaguer, S.; Parak, W. J.; Morales, M. P.; González, J. M.; Hernando, A.; De La Presa, P. Magnetic Capsules for NMR Imaging: Effect of Magnetic Nanoparticles Spatial Distribution and Aggregation. J. Phys. Chem. C 2011, 115 (14), 6257–6264.

(1) Herranz, F.; Almarza, E.; Rodríguez, I.; Salinas, B.; Rosell, Y.; Desco, M.; Bulte, J. W.; Ruiz-Cabello, J. The Application of Nanoparticles in Gene Therapy and Magnetic Resonance Imaging. Microsc. Res. Tech. 2011, 74 (7), 577–591.